脂滴研究--Perilipin（PLIN1-5）抗體一站式解決方案

近年來(lái)很多研究是關(guān)于脂滴（Lipid drops，LDs）與一些疾病的關(guān)系，比如脂肪肝、動(dòng)脈粥樣硬化、腎臟脂質(zhì)代謝紊亂、肥胖癥等。perilipin(PLIN)家族是目前研究較多的LDs結(jié)合蛋白。在哺乳動(dòng)物中PLIN家族共有五個(gè)成員，分別是perilipin, adipophilin,TIP47, S3-12 和MLDP/OXPAT ，也叫做 PLIN1-5 ，分布在身體的各個(gè)部位。

為了方便客戶，同時(shí)可以做多個(gè)指標(biāo)研究，Progen特意為客戶準(zhǔn)備了同時(shí)包含PLIN1-5抗體的set，更加節(jié)省成本。

發(fā)表文獻(xiàn)近百篇：

1 Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial function.Nature Communications . 2016

2 Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis.Nature Cell Biology.2015

3 Clinical and molecular characterization of a novel PLIN1 frameshift mutation identified in patients with familial partial lipodystrophy.Diabetes.2015

4 AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA.Autophagy.2016

5 Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling.Cell Reports.2013